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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   AVEN Antibody (N-term)   

AVEN Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AVEN Antibody (N-term) AP19959a
    AVEN Antibody (N-term) (Cat. #AP19959a) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the AVEN antibody detected the AVEN protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQS1
Other Accession NP_065104.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 78-106 aa
Additional Information
Other Names Cell death regulator Aven, AVEN
Target/Specificity This AVEN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the N-terminal region of human AVEN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAVEN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Protects against apoptosis mediated by Apaf-1.
Cellular Location Endomembrane system; Peripheral membrane protein. Note=Associated with intracellular membranes
Tissue Location Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas EMBL; AF283508; AAF91470.1; -; mRNA EMBL; BC010488; AAH10488.1; -; mRNA EMBL; BC063533; AAH63533.1; -; mRNA CCDS; CCDS10030.1; - RefSeq; NP_065104.1; NM_020371.2 UniGene; Hs.555966; - ProteinModelPortal; Q9NQS1; - BioGrid; 121366; 10 IntAct; Q9NQS1; 5 MINT; Q9NQS1; - STRING; 9606.ENSP00000306822; - iPTMnet; Q9NQS1; - PhosphoSitePlus; Q9NQS1; - BioMuta; AVEN; - DMDM; 20454834; - EPD; Q9NQS1; - jPOST; Q9NQS1; - MaxQB; Q9NQS1; - PaxDb; Q9NQS1; - PeptideAtlas; Q9NQS1; - PRIDE; Q9NQS1; - ProteomicsDB; 82177; - Ensembl; ENST00000306730; ENSP00000306822; ENSG00000169857 GeneID; 57099; - KEGG; hsa:57099; - UCSC; uc001zhj.4; human CTD; 57099; - DisGeNET; 57099; - EuPathDB; HostDB:ENSG00000169857.7; - GeneCards; AVEN; - HGNC; HGNC:13509; AVEN HPA; HPA020863; - MIM; 605265; gene neXtProt; NX_Q9NQS1; - OpenTargets; ENSG00000169857; - PharmGKB; PA134874337; - eggNOG; ENOG410IKTA; Eukaryota eggNOG; ENOG4111U7Z; LUCA GeneTree; ENSGT00390000003299; - HOGENOM; HOG000231429; - HOVERGEN; HBG024370; - InParanoid; Q9NQS1; - OMA; GMQLKGP; - OrthoDB; 1340211at2759; - PhylomeDB; Q9NQS1; - TreeFam; TF332067; - Reactome; R-HSA-111458; Formation of apoptosome Reactome; R-HSA-9627069; Regulation of the apoptosome activity ChiTaRS; AVEN; human GenomeRNAi; 57099; - PMAP-CutDB; Q9NQS1; - PRO; PR:Q9NQS1; - Proteomes; UP000005640; Chromosome 15 Bgee; ENSG00000169857; Expressed in 197 organ(s), highest expression level in heart left ventricle ExpressionAtlas; Q9NQS1; baseline and differential Genevisible; Q9NQS1; HS GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell GO; GO:0005622; C:intracellular; IDA:UniProtKB GO; GO:0016020; C:membrane; IDA:UniProtKB GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW GO; GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB InterPro; IPR026187; Aven PANTHER; PTHR16524; PTHR16524; 1 1: Evidence at protein level; Apoptosis; Complete proteome; Membrane; Methylation; Phosphoprotein; Polymorphism; Reference proteome CHAIN 1 362 Cell death regulator Aven /FTId=PRO_0000064768 COMPBIAS 5 85 Ala/Gly-rich MOD_RES 94 94 Phosphoserine MOD_RES 230 230 N6-methyllysine VARIANT 228 228 Q -> R (in dbSNP:rs2241647) /FTId=VAR_020144 SEQUENCE 362 AA; 38506 MW; D86517BA087232D4 CRC64; MQAERGARGG RGRRPGRGRP GGDRHSERPG AAAAVARGGG GGGGGDGGGR RGRGRGRGFR GARGGRGGGG APRGSRREPG GWGAGASAPV EDDSDAETYG EENDEQGNYS KRKIVSNWDR YQDIEKEVNN ESGESQRGTD FSVLLSSAGD SFSQFRFAEE KEWDSEASCP KQNSAFYVDS ELLVRALQEL PLCLRLNVAA ELVQGTVPLE VPQVKPKRTD DGKGLGMQLK GPLGPGGRGP IFELKSVAAG CPVLLGKDNP SPGPSRDSQK PTSPLQSAGD HLEEELDLLL NLDAPIKEGD NILPDQTSQD LKSKEDGEVV QEEEVCAKPS VTEEKNMEPE QPSTSKNVTE EELEDWLDSM IS
Research Areas
Citations (0)

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AVEN protects against apoptosis mediated by Apaf-1.


Bailey, S.D., et al. Diabetes Care (2010) In press :
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Sugarbaker, D.J., et al. Proc. Natl. Acad. Sci. U.S.A. 105(9):3521-3526(2008)

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$ 325.00
$ 109.00
Cat# AP19959a
Availability: In Stock
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