|Application ||WB, E|
|Calculated MW||66990 Da|
|Antigen Region||419-445 aa|
|Other Names||Protein GPR107, Lung seven transmembrane receptor 1, GPR107, KIAA1624, LUSTR1|
|Target/Specificity||This GPR107 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-445 amino acids from the C-terminal region of human GPR107.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR107 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins.|
|Cellular Location||Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
GPR107 is a G-protein coupled receptor which contains a carboxy-terminal seven transmembrane domain (LUSTR domain) similar to GPCRs. Three named isoforms exist.
Edgar, A.J. DNA Seq. 18(3):235-241(2007)
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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