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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SFXN1 Antibody (C-term)   

SFXN1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SFXN1 Antibody (C-term) AP20281b
    SFXN1 Antibody (C-term) (Cat. #AP20281b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SFXN1 antibody detected the SFXN1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H9B4
Other Accession NP_073591.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35619 Da
Antigen Region 293-321 aa
Additional Information
Gene ID 94081
Other Names Sideroflexin-1, Tricarboxylate carrier protein, TCC, SFXN1
Target/Specificity This SFXN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-321 amino acids from the C-terminal region of human SFXN1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSFXN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SFXN1 (HGNC:16085)
Function Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778). Transports both D-serine and L-serine (PubMed:30442778). Also able to transport other amino- acids, such as alanine (PubMed:30442778). May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity).
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Tissue Location Highly expressed in tissues with high one- carbon metabolism activity, such as blood, liver and kidney
Research Areas
Citations (0)

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Might be involved in the transport of a component required for iron utilization into or out of the mitochondria.


Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Siculella, L., et al. FEBS Lett. 578(3):280-284(2004)
Siculella, L., et al. J. Lipid Res. 45(7):1333-1340(2004)
Giudetti, A.M., et al. J. Lipid Res. 44(11):2135-2141(2003)
Miyake, S., et al. Biochem. Biophys. Res. Commun. 295(2):463-468(2002)

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$ 325.00
$ 109.00
Cat# AP20281b
Availability: In Stock
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