PHB Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
|Application ||WB, E|
|Other Accession||P67779, P67778, Q3T165, P24156|
|Predicted||Drosophila, Bovine, Mouse, Rat|
|Calculated MW||29804 Da|
|Other Names||Prohibitin, PHB|
|Target/Specificity||This PHB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 73-107 amino acids from the N-terminal region of human PHB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PHB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.|
|Cellular Location||Mitochondrion inner membrane.|
|Tissue Location||Widely expressed in different tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Sato T.,et al.Cancer Res. 52:1643-1646(1992).
Sato T.,et al.Genomics 17:762-764(1993).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (MAR-2005) to UniProtKB.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
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