|Application ||WB, E|
|Calculated MW||23434 Da|
|Other Names||Neuron-specific vesicular protein calcyon, CALY, DRD1IP|
|Target/Specificity||This CALY antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 60-94 amino acids from the N-terminal region of human CALY.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CALY Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.|
|Cellular Location||Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein|
|Tissue Location||Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non- schizophrenics.|
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Provided below are standard protocols that you may find useful for product applications.
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
Lezcano N.,et al.Science 287:1660-1664(2000).
Lezcano N.,et al.Science 314:1681-1681(2006).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Koh P.O.,et al.Arch. Gen. Psychiatry 60:311-319(2003).
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