|Application ||WB, E|
|Calculated MW||36435 Da|
|Other Names||Melanocortin receptor 4, MC4-R, mc4r|
|Target/Specificity||This DANRE mc4r antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the human region of DANRE mc4r.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(DANRE) mc4r Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Ringholm A.,et al.J. Neurochem. 82:6-18(2002).
Logan D.W.,et al.Genomics 81:184-191(2003).
Howe K.,et al.Nature 496:498-503(2013).
Sebag J.A.,et al.Science 341:278-281(2013).
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