|Application ||WB, E|
|Calculated MW||48608 Da|
|Other Names||Myc-associated zinc finger protein, MAZI, Pur-1, Purine-binding transcription factor, Serum amyloid A-activating factor-1, SAF-1, Transcription factor Zif87, ZF87, Zinc finger protein 801, MAZ, ZNF801|
|Target/Specificity||This MAZ antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 295-327 amino acids from the Central region of human MAZ.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAZ Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.|
|Cellular Location||Nucleus. Note=In brains of Alzheimer disease patients, present in a plaque- like structures|
|Tissue Location||Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Bossone S.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992).
Pyrc J.J.,et al.Biochemistry 31:4102-4110(1992).
Tsutsui H.,et al.Biochem. Biophys. Res. Commun. 226:801-809(1996).
Parks C.L.,et al.J. Biol. Chem. 271:4417-4430(1996).
Song J.,et al.J. Biol. Chem. 273:20603-20614(1998).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.