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SAPCD2 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SAPCD2 Antibody (C-Term) AP21936b
    All lanes : Anti-SAPCD2 Antibody (C-Term) at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: PC-3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86UD0
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 42637 Da
Additional Information
Gene ID 89958
Other Names Suppressor APC domain-containing protein 2, Tumor specificity and mitosis phase-dependent expression protein, TS/MDEP, p42.3, SAPCD2, C9orf140
Target/Specificity This SAPCD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 333-367 amino acids from human SAPCD2.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSAPCD2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAPCD2 (HGNC:28055)
Synonyms C9orf140
Function Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (By similarity). Negatively regulates the mitotic apical cortex localization of GPSM2 (PubMed:26766442). Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:23576022, PubMed:23704824).
Cellular Location Cytoplasm. Nucleus. Cytoplasm, cell cortex. Apical cell membrane {ECO:0000250|UniProtKB:Q9D818}. Cell junction, tight junction. Note=Localized at the apical cortical region during the M phase. In horizontally retinal progenitor dividing cells, localized at the pole cortical region from prophase to telophase cells. In vertically retinal progenitor dividing cells, not detected at the pole cortical region at any stage of mitosis. {ECO:0000250|UniProtKB:Q9D818}
Tissue Location Expressed in 5-month-old fetal tissues, including stomach, intestine, colon, liver, brain, lung, heart, spleen and kidney (PubMed:17525738). Undetectable in non-cancerous adult tissues (PubMed:17525738). Expressed in many primary gastric carcinoma, but almost not in adjacent normal mucosa (PubMed:17525738). Expressed preferentially in M and G1 phases, compared to S and G2 phases (PubMed:17525738). Expression is up- regulated in hepatocellular carcinoma (HCC) and colorectal cancer (CRC) tissues (at protein level) (PubMed:23704824)
Research Areas
Citations (0)

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Xu X.,et al.Oncogene 26:7371-7379(2007).
Humphray S.J.,et al.Nature 429:369-374(2004).

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$ 325.00
$ 109.00
Cat# AP21936b
Availability: In Stock
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