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Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, E |
|---|---|
| Primary Accession | Q9UHD4 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit Ig |
| Other Names | Cell death activator CIDE-B, Cell death-inducing DFFA-like effector B, CIDEB |
|---|---|
| Target/Specificity | This CIDEB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-183 amino acids from human CIDEB. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CIDEB Antibody (C-erm) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CIDEB |
|---|---|
| Function | Activates apoptosis. |
| Tissue Location | Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen EMBL; AF190901; AAF23324.1; -; mRNA EMBL; AF218586; AAF27658.1; -; mRNA EMBL; AF544398; AAN37907.1; -; mRNA EMBL; AK000387; BAA91132.1; -; mRNA EMBL; CH471078; EAW66031.1; -; Genomic_DNA EMBL; CH471078; EAW66032.1; -; Genomic_DNA EMBL; CH471078; EAW66033.1; -; Genomic_DNA EMBL; BC035970; AAH35970.1; -; mRNA CCDS; CCDS32056.1; - RefSeq; NP_001305736.1; NM_001318807.1 RefSeq; NP_055245.2; NM_014430.2 RefSeq; XP_011534961.1; XM_011536659.2 RefSeq; XP_016876710.1; XM_017021221.1 UniGene; Hs.642693; - UniGene; Hs.708040; - PDB; 1D4B; NMR; -; A=1-116 PDBsum; 1D4B; - ProteinModelPortal; Q9UHD4; - SMR; Q9UHD4; - BioGrid; 118027; 9 IntAct; Q9UHD4; 62 STRING; 9606.ENSP00000258807; - iPTMnet; Q9UHD4; - PhosphoSitePlus; Q9UHD4; - BioMuta; CIDEB; - DMDM; 20141283; - EPD; Q9UHD4; - PaxDb; Q9UHD4; - PeptideAtlas; Q9UHD4; - PRIDE; Q9UHD4; - ProteomicsDB; 84324; - DNASU; 27141; - Ensembl; ENST00000258807; ENSP00000258807; ENSG00000136305 Ensembl; ENST00000336557; ENSP00000337731; ENSG00000136305 Ensembl; ENST00000554411; ENSP00000451089; ENSG00000136305 Ensembl; ENST00000642223; ENSP00000493738; ENSG00000285199 Ensembl; ENST00000644519; ENSP00000494868; ENSG00000285199 Ensembl; ENST00000644672; ENSP00000495235; ENSG00000285199 GeneID; 27141; - KEGG; hsa:27141; - UCSC; uc001won.4; human CTD; 27141; - DisGeNET; 27141; - EuPathDB; HostDB:ENSG00000136305.11; - GeneCards; CIDEB; - HGNC; HGNC:1977; CIDEB HPA; HPA001272; - MIM; 604441; gene neXtProt; NX_Q9UHD4; - OpenTargets; ENSG00000136305; - PharmGKB; PA26515; - eggNOG; ENOG410IIBQ; Eukaryota eggNOG; ENOG4111N1Y; LUCA GeneTree; ENSGT00390000018596; - HOGENOM; HOG000029211; - HOVERGEN; HBG050961; - InParanoid; Q9UHD4; - OMA; VWTSAPP; - OrthoDB; EOG091G0KVY; - PhylomeDB; Q9UHD4; - TreeFam; TF334321; - SignaLink; Q9UHD4; - ChiTaRS; CIDEB; human EvolutionaryTrace; Q9UHD4; - GenomeRNAi; 27141; - PRO; PR:Q9UHD4; - Proteomes; UP000005640; Chromosome 14 Bgee; ENSG00000136305; - CleanEx; HS_CIDEB; - ExpressionAtlas; Q9UHD4; baseline and differential Genevisible; Q9UHD4; HS GO; GO:0005829; C:cytosol; IDA:MGI GO; GO:0005811; C:lipid droplet; IBA:GO_Central GO; GO:0048471; C:perinuclear region of cytoplasm; IDA:AgBase GO; GO:0042802; F:identical protein binding; IPI:IntAct GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:AgBase GO; GO:0006915; P:apoptotic process; IDA:MGI GO; GO:0097194; P:execution phase of apoptosis; ISS:BHF-UCL GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; TAS:ProtInc GO; GO:0010942; P:positive regulation of cell death; IDA:AgBase GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:AgBase InterPro; IPR003508; CIDE-N_dom Pfam; PF02017; CIDE-N; 1 SMART; SM00266; CAD; 1 PROSITE; PS51135; CIDE_N; 1 1: Evidence at protein level; 3D-structure; Apoptosis; Complete proteome; Reference proteome CHAIN 1 219 Cell death activator CIDE-B /FTId=PRO_0000144720 DOMAIN 34 110 CIDE-N. {ECO:0000255|PROSITE- ProRule:PRU00447} CONFLICT 120 120 L -> P (in Ref. 1; AAF23324) CONFLICT 124 124 R -> S (in Ref. 1; AAF23324) CONFLICT 132 132 A -> G (in Ref. 1; AAF23324) STRAND 9 12 {ECO:0000244|PDB:1D4B} STRAND 36 41 {ECO:0000244|PDB:1D4B} STRAND 43 46 {ECO:0000244|PDB:1D4B} STRAND 48 53 {ECO:0000244|PDB:1D4B} HELIX 59 67 {ECO:0000244|PDB:1D4B} STRAND 74 77 {ECO:0000244|PDB:1D4B} TURN 78 81 {ECO:0000244|PDB:1D4B} STRAND 82 84 {ECO:0000244|PDB:1D4B} HELIX 88 92 {ECO:0000244|PDB:1D4B} STRAND 93 95 {ECO:0000244|PDB:1D4B} SEQUENCE 219 AA; 24678 MW; E0B4E5EF1F7C912D CRC64; MEYLSALNPS DLLRSVSNIS SEFGRRVWTS APPPQRPFRV CDHKRTIRKG LTAATRQELL AKALETLLLN GVLTLVLEED GTAVDSEDFF QLLEDDTCLM VLQSGQSWSP TRSGVLSYGL GRERPKHSKD IARFTFDVYK QNPRDLFGSL NVKATFYGLY SMSCDFQGLG PKKVLRELLR WTSTLLQGLG HMLLGISSTL RHAVEGAEQW QQKGRLHSY |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Activates apoptosis.
References
Lugovskoy A.A.,et al.Cell 99:747-755(1999).
Inohara N.,et al.EMBO J. 17:2526-2533(1998).
Liang L.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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$ 325.00
$ 109.00
Cat# AP21953a
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