|Application ||WB, E|
|Calculated MW||37948 Da|
|Other Names||Cytosolic 5'-nucleotidase 3A, 22.214.171.124, Cytosolic 5'-nucleotidase 3, Cytosolic 5'-nucleotidase III, cN-III, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I, Uridine 5'-monophosphate hydrolase 1, p36, NT5C3A, NT5C3, P5N1, UMPH1|
|Target/Specificity||This NT5C3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-313 amino acids from human NT5C3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NT5C3, P5N1, UMPH1|
|Function||Nucleotidase which shows specific activity towards cytidine monophosphate (CMP) and 7-methylguanosine monophosphate (m(7)GMP) (PubMed:24603684). CMP seems to be the preferred substrate (PubMed:15968458).|
|Tissue Location||Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Can act both as nucleotidase and as phosphotransferase.
Amici A.,et al.Blood 96:1596-1598(2000).
Marinaki A.M.,et al.Blood 97:3327-3332(2001).
Kanno H.,et al.Br. J. Haematol. 126:265-271(2004).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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