PIGC Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
|Application ||FC, WB, E|
|Other Accession||Q3ZBX1, Q9CXR4, Q5PQQ4|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||33583 Da|
|Other Names||Phosphatidylinositol N-acetylglucosaminyltransferase subunit C, 220.127.116.11, Phosphatidylinositol-glycan biosynthesis class C protein, PIG-C, PIGC, GPI2|
|Target/Specificity||This PIGC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 264-294 amino acids from human PIGC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PIGC Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in GPI anchor biosynthesis (PubMed:8806613, PubMed:27694521). Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis (ECO:0000269|PubMed:27694521).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Inoue N.,et al.Biochem. Biophys. Res. Commun. 226:193-199(1996).
Hong Y.,et al.Genomics 44:347-349(1997).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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