|Application ||WB, E|
|Calculated MW||51122 Da|
|Other Names||Tubulin gamma-2 chain, Gamma-2-tubulin, Tubg2|
|Target/Specificity||This gamma Tubulin antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 400-434 amino acids from the mouse region of mouse gamma Tubulin.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||gamma Tubulin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Mainly localizes to the centrosome, but a fraction is found outside of the centrosome in the cytoplasm|
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Provided below are standard protocols that you may find useful for product applications.
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
Alvarado-Kristensson M.,et al.Nat. Cell Biol. 11:1081-1092(2009).
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