- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||36335 Da|
|Antigen Region||210-240 aa|
|Other Names||GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1, ADP-ribosyltransferase C2 and C3 toxin-like 1, ARTC1, Mono(ADP-ribosyl)transferase 1, CD296, ART1|
|Target/Specificity||This ART1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the Central region of human ART1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ART1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has ADP-ribosyltransferase activity toward GLP1R.|
|Cellular Location||Sarcoplasmic reticulum membrane; Lipid- anchor, GPI-anchor|
Provided below are standard protocols that you may find useful for product applications.
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence of ART1 consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins.
Koch-Nolte, F., et al., Genomics 39(3):370-376 (1997). Koch-Nolte, F., et al., Genomics 36(1):215-216 (1996). Okazaki, I.J., et al., Biochemistry 33(43):12828-12836 (1994).
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