|Application ||WB, IHC-P, E|
|Calculated MW||78366 Da|
|Antigen Region||615-649 aa|
|Other Names||Caprin-1, Cell cycle-associated protein 1, Cytoplasmic activation- and proliferation-associated protein 1, GPI-anchored membrane protein 1, GPI-anchored protein p137, GPI-p137, p137GPI, Membrane component chromosome 11 surface marker 1, RNA granule protein 105, CAPRIN1, GPIAP1, GPIP137, M11S1, RNG105|
|Target/Specificity||This GPIP137 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-649 amino acids from the C-terminal region of human GPIP137.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPIP137 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPIAP1, GPIP137, M11S1, RNG105|
|Function||May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.|
|Cellular Location||Cytoplasm, cytosol. Cell projection, dendrite. Note=Associated with RNA granules.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GPIP137 may regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. It is expressed in the cytoplasm.
Gessler, M., et al., Genomics 32(1):169-170 (1996).
Ellis, J.A., et al., J. Biol. Chem. 270(35):20717-20723 (1995).
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