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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CPT1A Antibody (C-term)   

CPT1A Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CPT1A Antibody (C-term) AP2524b
    Western blot analysis of anti-CPT1A Pab (Cat. #AP2524b) in Y79 cell line lysate (35ug/lane). CPT1A(arrow) was detected using the purified Pab.
  • IHC-P - CPT1A Antibody (C-term) AP2524b
    Left image is paraformaldehyde-fixed and paraffin-embedded cow lactating with CPT1A Pab (Cat. #AP2524b), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining, right image is contrast, did not add the antibody. This data was kindly offered by Hideaki Hayashi, University of Bern, Switzerland.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P50416
Reactivity Bovine, Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 88368 Da
Antigen Region 606-636 aa
Additional Information
Gene ID 1374
Other Names Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A, CPT1A, CPT1
Target/Specificity This CPT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-636 amino acids from the C-terminal region of human CPT1A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCPT1A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CPT1A
Synonyms CPT1
Function Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.
Cellular Location Mitochondrion outer membrane; Multi- pass membrane protein
Tissue Location Strong expression in kidney and heart, and lower in liver and skeletal muscle
Research Areas
Citations (0)

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The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.


Rasmussen, B.B., et al., J. Clin. Invest. 110(11):1687-1693 (2002).
Ogawa, E., et al., J. Hum. Genet. 47(7):342-347 (2002).
Cook, G.A., et al., Am. J. Med. Sci. 318(1):43-48 (1999).
IJlst, L., et al., J. Clin. Invest. 102(3):527-531 (1998).
Britton, C.H., et al., Genomics 40(1):209-211 (1997).

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Cat# AP2524b
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