- CITATIONS: 2
|Application ||WB, IHC-P, E|
|Other Accession||Q91VC0, Q9QY93|
|Calculated MW||18681 Da|
|Antigen Region||12-40 aa|
|Other Names||dCTP pyrophosphatase 1, Deoxycytidine-triphosphatase 1, dCTPase 1, RS21C6, XTP3-transactivated gene A protein, DCTPP1, XTP3TPA|
|Target/Specificity||This XTP3TPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human XTP3TPA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||XTP3TPA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.|
|Cellular Location||Mitochondrion. Nucleus. Cytoplasm, cytosol|
Provided below are standard protocols that you may find useful for product applications.
Stelzl,U., Cell 122 (6), 957-968 (2005)
Moroz,O.V., J. Mol. Biol. 347 (2), 243-255 (2005)
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