PAX3 Antibody (N-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
|Application ||WB, IHC-P, FC, E|
|Other Accession||P47239, P23759, P24610|
|Calculated MW||52968 Da|
|Antigen Region||98-126 aa|
|Other Names||Paired box protein Pax-3, HuP2, PAX3, HUP2|
|Target/Specificity||This PAX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human PAX3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAX3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 (PubMed:21965087).|
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Provided below are standard protocols that you may find useful for product applications.
PAX3 probable is a transcription factor associated with development of alveolar rhabdomyosarcoma.
Boutet,S.C., et.al., Cell 130 (2), 349-362 (2007)
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