RDH10 Antibody (Center)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
|Application ||WB, IHC-P, FC, E|
|Other Accession||Q80ZF7, Q8VCH7, Q8HZT6|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||38087 Da|
|Antigen Region||106-135 aa|
|Other Names||Retinol dehydrogenase 10, RDH10|
|Target/Specificity||This RDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the Central region of human RDH10.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RDH10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.|
|Cellular Location||Microsome membrane; Single- pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
RDH10 generates all-trans retinal from all-trans retinol and may plan an important role in the photic visual cycle. All-trans retinal is isomerized to 11-cis retinal by the retinal G protein-coupled receptor (RGR; MIM 600342) when the retinal pigment epithelium (RPE) is illuminated.
Bankovic, J., et al. Lung Cancer 67(2):151-159(2010)
Takahashi, Y., et al. Biochem. J. 419(1):113-122(2009)
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009)
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