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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| WB, FC, E |
|---|---|
| Primary Accession | A2VDJ0 |
| Other Accession | NP_056011 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Calculated MW | 179339 Da |
| Antigen Region | 1266-1295 aa |
| Gene ID | 23240 |
|---|---|
| Other Names | Transmembrane protein 131-like, KIAA0922, TMEM131L |
| Target/Specificity | This T131L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1266-1295 amino acids from the C-terminal region of human T131L. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | T131L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TMEM131L (HGNC:29146) |
|---|---|
| Function | Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=During intrathymic development, resides in punctate cytoplasmic structures in DN1 and DN2 cells. In DN3 cells, found in large crescent-shaped membrane structures, which preferentially localize in cell-to-cell contact zones. Isoform 5: Cytoplasm. Note=Scattered throughout the cytoplasm in small-sized punctate structures |
| Tissue Location | Expressed in thymocytes. |
Research Areas
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Application Protocols
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Cat# AP4964b
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