|Reactivity||Human, Mouse, Rat|
|Calculated MW||43 KDa|
|Antigen Region||288-317 aa|
|Other Names||cAMP-dependent protein kinase type I-alpha regulatory subunit, Tissue-specific extinguisher 1, TSE1, cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed, PRKAR1A, PKR1, PRKAR1, TSE1|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Synonyms||PKR1, PRKAR1, TSE1|
|Function||Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.|
|Cellular Location||Cell membrane.|
|Tissue Location||Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible|
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Provided below are standard protocols that you may find useful for product applications.
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
Sandberg M.,et al.Biochem. Biophys. Res. Commun. 149:939-945(1987).
Sandberg M.,et al.Biochem. Biophys. Res. Commun. 167:323-330(1990).
Jones K.W.,et al.Cell 66:861-872(1991).
Solberg R.,et al.Endocrinology 138:169-181(1997).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
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