|Application ||WB, IF, IHC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||81,70,84 KDa|
|Antigen Region||705-734 aa|
|Other Names||Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit|
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Provided below are standard protocols that you may find useful for product applications.
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
Joshi R.L.,et al.J. Cell Biol. 115:665-675(1991).
Lin B.,et al.Genomics 25:93-99(1995).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Taylor S.A.,et al.Nat. Genet. 2:223-227(1992).
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