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Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | O75751 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 61 KDa |
| Antigen Region | 282-310 aa |
| Gene ID | 6581 |
|---|---|
| Other Names | Solute carrier family 22 member 3, Extraneuronal monoamine transporter, EMT, Organic cation transporter 3, SLC22A3, EMTH, OCT3 |
| Dilution | WB~~ 1:1000 |
| Format | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Conditions | -20℃ |
| Name | SLC22A3 |
|---|---|
| Synonyms | EMTH, OCT3 |
| Function | Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
References
Gruendemann D.,et al.Nat. Neurosci. 1:349-351(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Verhaagh S.,et al.Genomics 55:209-218(1999).
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