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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   LILRA1 Antibody   

LILRA1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LILRA1 Antibody AP50711
    Western blot analysis of lysate from HL-60 cell line,using LILRA1 Antibody(AP50711). AP50711 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
  • IF - LILRA1 Antibody AP50711
    Immunofluorescence analysis of A549 cells, using LILRA1 antibody.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession O75019
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 53,32 KDa
Antigen Region 58-89 aa
Additional Information
Other Names Leukocyte immunoglobulin-like receptor subfamily A member 1, CD85 antigen-like family member I, Leukocyte immunoglobulin-like receptor 6, LIR-6, CD85i, LILRA1, LIR6
Dilution WB~~1:1000
IF~~1:100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name LILRA1
Synonyms LIR6
Function May act as receptor for class I MHC antigens.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Detected in monocytes and B-cells. EMBL; AF025529; AAB87663.1; -; mRNA EMBL; AF025530; AAB87664.1; -; mRNA EMBL; BC101514; AAI01515.1; -; mRNA CCDS; CCDS12901.1; -. [O75019-1] CCDS; CCDS62802.1; -. [O75019-2] RefSeq; NP_001265247.1; NM_001278318.1. [O75019-2] RefSeq; NP_001265248.1; NM_001278319.1 RefSeq; NP_006854.1; NM_006863.3. [O75019-1] UniGene; Hs.710507; - ProteinModelPortal; O75019; - SMR; O75019; - BioGrid; 116214; 1 STRING; 9606.ENSP00000251372; - iPTMnet; O75019; - PhosphoSitePlus; O75019; - PaxDb; O75019; - PeptideAtlas; O75019; - PRIDE; O75019; - ProteomicsDB; 49694; - ProteomicsDB; 49695; -. [O75019-2] Ensembl; ENST00000251372; ENSP00000251372; ENSG00000104974. [O75019-1] Ensembl; ENST00000453777; ENSP00000413715; ENSG00000104974. [O75019-2] Ensembl; ENST00000617170; ENSP00000477637; ENSG00000275525. [O75019-1] Ensembl; ENST00000620606; ENSP00000478666; ENSG00000275525. [O75019-2] Ensembl; ENST00000628480; ENSP00000487229; ENSG00000277398. [O75019-2] Ensembl; ENST00000631007; ENSP00000487011; ENSG00000274935. [O75019-2] GeneID; 11024; - KEGG; hsa:11024; - UCSC; uc002qgh.4; human. [O75019-1] CTD; 11024; - DisGeNET; 11024; - EuPathDB; HostDB:ENSG00000104974.10; - GeneCards; LILRA1; - HGNC; HGNC:6602; LILRA1 MIM; 604810; gene neXtProt; NX_O75019; - OpenTargets; ENSG00000104974; - PharmGKB; PA30376; - eggNOG; ENOG410IKJD; Eukaryota eggNOG; ENOG41116BR; LUCA GeneTree; ENSGT00760000119033; - HOGENOM; HOG000234395; - HOVERGEN; HBG074353; - InParanoid; O75019; - KO; K06512; - OMA; NFSITHM; - OrthoDB; EOG091G020P; - PhylomeDB; O75019; - TreeFam; TF336644; - Reactome; R-HSA-198933; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell ChiTaRS; LILRA1; human GenomeRNAi; 11024; - PRO; PR:O75019; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000104974; - CleanEx; HS_LILRA1; - Genevisible; O75019; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0005886; C:plasma membrane; TAS:Reactome GO; GO:0003823; F:antigen binding; TAS:ProtInc GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc GO; GO:0006952; P:defense response; TAS:ProtInc GO; GO:0050776; P:regulation of immune response; TAS:Reactome Gene3D; 2.60.40.10; -; 4 InterPro; IPR016332; A1B_glyco/leuk_Ig-like_rcpt InterPro; IPR007110; Ig-like_dom InterPro; IPR036179; Ig-like_dom_sf InterPro; IPR013783; Ig-like_fold InterPro; IPR003599; Ig_sub InterPro; IPR003598; Ig_sub2 Pfam; PF13895; Ig_2; 2 PIRSF; PIRSF001979; Alpha_1B_glycoprot_prd; 1 SMART; SM00409; IG; 4 SMART; SM00408; IGc2; 3 SUPFAM; SSF48726; SSF48726; 4 PROSITE; PS50835; IG_LIKE; 1 2: Evidence at transcript level; Adaptive immunity; Alternative splicing; Complete proteome; Disulfide bond; Glycoprotein; Immunity; Immunoglobulin domain; Membrane; Polymorphism; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix SIGNAL 1 16 CHAIN 17 489 Leukocyte immunoglobulin-like receptor subfamily A member 1 /FTId=PRO_0000014816 TOPO_DOM 17 461 Extracellular. TRANSMEM 462 482 Helical. TOPO_DOM 483 489 Cytoplasmic. DOMAIN 27 116 Ig-like C2-type 1 DOMAIN 119 224 Ig-like C2-type 2 DOMAIN 226 315 Ig-like C2-type 3 DOMAIN 326 415 Ig-like C2-type 4 CARBOHYD 140 140 N-linked (GlcNAc...) asparagine CARBOHYD 281 281 N-linked (GlcNAc...) asparagine CARBOHYD 302 302 N-linked (GlcNAc...) asparagine CARBOHYD 341 341 N-linked (GlcNAc...) asparagine CARBOHYD 431 431 N-linked (GlcNAc...) asparagine CARBOHYD 448 448 N-linked (GlcNAc...) asparagine DISULFID 49 98 {ECO:0000255|PROSITE-ProRule:PRU00114} DISULFID 145 197 {ECO:0000255|PROSITE-ProRule:PRU00114} DISULFID 157 167 {ECO:0000255|PROSITE-ProRule:PRU00114} DISULFID 246 297 {ECO:0000255|PROSITE-ProRule:PRU00114} DISULFID 346 397 {ECO:0000255|PROSITE-ProRule:PRU00114} VAR_SEQ 221 420 Missing (in isoform 2) /FTId=VSP_008454 VARIANT 12 12 R -> G (in dbSNP:rs1974982) /FTId=VAR_059396 VARIANT 153 153 S -> G (in dbSNP:rs10417589) /FTId=VAR_049886 VARIANT 220 220 L -> P (in dbSNP:rs373854) /FTId=VAR_049887 CONFLICT 5 5 V -> L (in Ref. 1; AAB87663) SEQUENCE 489 AA; 53275 MW; 44469FD4884EA068 CRC64; MTPIVTVLIC LRLSLGPRTH VQAGTLPKPT LWAEPGSVIT QGSPVTLWCQ GILETQEYRL YREKKTAPWI TRIPQEIVKK GQFPIPSITW EHTGRYRCFY GSHTAGWSEP SDPLELVVTG AYIKPTLSAL PSPVVTSGGN VTLHCVSQVA FGSFILCKEG EDEHPQCLNS QPRTHGWSRA IFSVGPVSPS RRWSYRCYAY DSNSPHVWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPGE SLTLQCVSDV SYDRFVLYKE GERDFLQLPG PQPQAGLSQA NFTLGPVSRS YGGQYRCSGA YNLSSEWSAP SDPLDILIAG QFRGRPFISV HPGPTVASGE NVTLLCQSWG PFHTFLLTKA GAADAPLRLR SIHEYPKYQA EFPMSPVTSA HSGTYRCYGS LSSNPYLLSH PSDSLELMVS GAAETLSPPQ NKSDSKAGAA NTLSPSQNKT ASHPQDYTVE NLIRMGIAGL VLVVLGILLF EAQHSQRSL
Research Areas
Citations (0)

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Background

May act as receptor for class I MHC antigens.

References

Borges L.,et al.J. Immunol. 159:5192-5196(1997).

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$ 325.00
Cat# AP50711
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