|Calculated MW||37 KDa|
|Other Names||I18BP_HUMAN;IL-18BP;IL18 BP;IL18 BPa;IL18BP;IL18BPa;Interleukin 18 binding protein; Interleukin-18-binding protein;MC51L 53L 54L homolog gene product;Tadekinig alfa; Tadekinig-alfa.|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.|
|Tissue Location||Strongly expressed in heart, lung, placenta and spleen.|
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Provided below are standard protocols that you may find useful for product applications.
Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response.
Novick D.,et al.Immunity 10:127-136(1999).
Aizawa Y.,et al.FEBS Lett. 445:338-342(1999).
Xiang Y.,et al.Virology 257:297-302(1999).
Kim S.-H.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:1190-1195(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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