|Application ||WB, FC, E|
|Other Accession||Q9JKU3, Q6VH22, NP_056477.1|
|Calculated MW||197576 Da|
|Antigen Region||28-57 aa|
|Other Names||Intraflagellar transport protein 172 homolog, IFT172, KIAA1179|
|Target/Specificity||This IFT172 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human IFT172.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IFT172 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity).|
|Cellular Location||Cell projection, cilium. Note=Localized to the axoneme and around the base of the cilium|
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Howard, P.W., et al. J. Biol. Chem. 275(18):13336-13342(2000)
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