|Application ||WB, IHC-P, E|
|Calculated MW||46885 Da|
|Antigen Region||25-52 aa|
|Other Names||Synaptotagmin-13, Synaptotagmin XIII, SytXIII, SYT13, KIAA1427|
|Target/Specificity||This SYT13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human SYT13.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SYT13 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in transport vesicle docking to the plasma membrane.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Expressed in brain, pancreas and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
SYT13 belongs to the large synaptotagmin protein family. All synaptotagmins show type I membrane topology, with an extracellular N terminus, a single transmembrane region, and a cytoplasmic C terminus containing tandem C2 domains. Major functions of synaptotagmins include vesicular traffic, exocytosis, and secretion.
Jahn, J.E., et al. Int. J. Oncol. 32(2):441-449(2008)
Craxton, M. Genomics 77 (1-2), 43-49 (2001) :
Fukuda, M., et al. Biochem. J. 354 (PT 2), 249-257 (2001) :
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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