|Application ||FC, IF, IHC-P, WB, E|
|Other Accession||P00325, P07327, NP_000660.1|
|Calculated MW||39868 Da|
|Antigen Region||231-260 aa|
|Other Names||Alcohol dehydrogenase 1C, Alcohol dehydrogenase subunit gamma, ADH1C, ADH3|
|Target/Specificity||This ADH1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human ADH1C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ADH1C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster.
Benzon Larsen, S., et al. Cancer Lett. (2010) In press :
Sangrajrang, S., et al. Breast Cancer Res. Treat. (2010)
Khan, A.J., et al. Drug Alcohol Depend (2010) In press :
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