AGXT Antibody (Center)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
|Application ||WB, IHC-P, FC, E|
|Calculated MW||43010 Da|
|Antigen Region||96-125 aa|
|Other Names||Serine--pyruvate aminotransferase, SPT, Alanine--glyoxylate aminotransferase, AGT, AGXT, AGT1, SPAT|
|Target/Specificity||This AGXT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human AGXT.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AGXT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Peroxisome. Mitochondrion Note=Predominantly localized in the peroxisomes. Mitochondrial mistargeting occurs in variant proteins Arg-41, Arg-47, Ile-152, Arg-170 and Thr-244 associated with the disease HP1|
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Provided below are standard protocols that you may find useful for product applications.
AGXT is expressed only in the liver and protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification.
Cellini,B., J. Biol. Chem. 284 (13), 8349-8358 (2009)
Bertoldi,M., Biochim. Biophys. Acta 1784 (9), 1356-1362 (2008)
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