|Application ||FC, IHC-P, WB, E|
|Other Accession||Q68FR9, P57776, Q4R3D4|
|Predicted||Monkey, Mouse, Rat|
|Calculated MW||31122 Da|
|Antigen Region||1-30 aa|
|Other Names||Elongation factor 1-delta, EF-1-delta, Antigen NY-CO-4, EEF1D, EF1D|
|Target/Specificity||This EEF1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EEF1D.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EEF1D Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1- alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.|
|Cellular Location||Isoform 2: Nucleus|
|Tissue Location||Isoform 2 is specifically expressed in brain, cerebellum and testis|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
EEF1D is a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs.
Yang,S., BMC Cancer 7, 211 (2007)
Mulner-Lorillon,O., J. Biol. Chem. 269 (31), 20201-20207 (1994)
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