|Application ||WB, FC, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||51676 Da|
|Antigen Region||200-227 aa|
|Other Names||Hemopexin, Beta-1B-glycoprotein, HPX|
|Target/Specificity||This HPX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the Central region of human HPX.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HPX Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
HPX is a plasma glycoprotein that binds heme with high affinity. The protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress.
Ascenzi,P., IUBMB Life 59 (11), 700-708 (2007)
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