|Application ||FC, IHC-P, WB, E|
|Calculated MW||22180 Da|
|Antigen Region||159-188 aa|
|Other Names||Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase FKBP11, 19 kDa FK506-binding protein, 19 kDa FKBP, FKBP-19, FK506-binding protein 11, FKBP-11, Rotamase, FKBP11, FKBP19|
|Target/Specificity||This FKBP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the C-terminal region of human FKBP11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FKBP11 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins during protein synthesis.|
|Cellular Location||Membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin.
Rulten,S.L., et.al., Mamm. Genome 17 (4), 322-331 (2006)
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