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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   COLEC11 Antibody (N-term)   

COLEC11 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - COLEC11 Antibody (N-term) AP6840a
    Western blot analysis of COLEC11 Antibody (N-term) (Cat. #AP6840a) in MDA-MB231 cell line lysates (35ug/lane). COLEC11 (arrow) was detected using the purified Pab.
  • IHC-P - COLEC11 Antibody (N-term) AP6840a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma with COLEC11 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - COLEC11 Antibody (N-term) AP6840a
    Flow cytometric analysis of MDA-231 cells using COLEC11 Antibody (N-term)(bottom histogram) compared to a negative control (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - COLEC11 Antibody (N-term) AP6840a
    Western blot analysis of COLEC11 (arrow) using rabbit polyclonal COLEC11 Antibody (N-term) (Cat. #AP6840a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the COLEC11 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BWP8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28665 Da
Antigen Region 50-78 aa
Additional Information
Gene ID 78989
Other Names Collectin-11, Collectin kidney protein 1, CL-K1, COLEC11
Target/Specificity This COLEC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human COLEC11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOLEC11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COLEC11
Function Lectin that plays a role in innate immunity, apoptosis and embryogenesis (PubMed:23954398, PubMed:25912189, PubMed:21258343). Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope (PubMed:25912189). Primarily recognizes the terminal disaccharide of the glycan (PubMed:25912189). Also recognizes a subset of fucosylated glycans and lipopolysaccharides (PubMed:17179669, PubMed:25912189). Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 (PubMed:20956340, PubMed:25912189). Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed:21258343, PubMed:28301481).
Cellular Location Secreted.
Tissue Location Ubiquitous (PubMed:17179669). Detected in adrenal gland, kidney, liver, ovaries and testis (at protein level) (PubMed:20956340).
Research Areas
Citations (0)

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COLEC11 is a member of the collectin family of C-type lectins, which contain a collagen-like domain and a carbohydrate recognition domain, and play a role in host-defense


Oguri,M.,, Am. J. Hypertens. (2009)

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$ 325.00
$ 109.00
Cat# AP6840a
Availability: In Stock
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