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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term)   

Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term) AP7134A
    Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term) (Cat.#AP7134a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies).
  • IHC-P - Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term) AP7134A
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • WB - Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term) AP7134A
    Western blot analysis of anti-GUCY1A3 Pab (Cat. #AP7134a) in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02108
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 77452 Da
Antigen Region 269-300 aa
Additional Information
Gene ID 2982
Other Names Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3, GUC1A3, GUCSA3, GUCY1A1
Target/Specificity This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGuanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUCY1A1 (HGNC:4685)
Cellular Location Cytoplasm.
Tissue Location Detected in brain cortex and lung (at protein level).
Research Areas
Citations ( 0 )


Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.


Saino, M., et al., Oncol. Rep. 12(1):47-52 (2004).
Zhou, Y., et al., Gene 245(2):319-328 (2000).
Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).
Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).
Giuili, G., et al., FEBS Lett. 304(1):83-88 (1992).

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$ 325.00
$ 109.00
Cat# AP7134A
Availability: In Stock
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