|Application ||WB, IHC-P, E|
|Calculated MW||49955 Da|
|Antigen Region||318-345 aa|
|Other Names||Thymidine phosphorylase, TP, Gliostatin, Platelet-derived endothelial cell growth factor, PD-ECGF, TdRPase, TYMP, ECGF1|
|Target/Specificity||This ECGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-345 amino acids from the Central region of human ECGF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ECGF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.|
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Provided below are standard protocols that you may find useful for product applications.
ECGF1 is an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in the gene encoding ECGF1 have been associated with mitochondrial neurogastrointestinal encephalomyopathy.
Stenman,G.,Cytogenet. Cell Genet. 59 (1), 22-23 (1992)
Jinfeng,M.,Hepatogastroenterology 54 (78), 1635-1640 (2007)
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