|Application ||WB, E|
|Calculated MW||74975 Da|
|Antigen Region||399-428 aa|
|Other Names||Uncharacterized protein C18orf8, Colon cancer-associated protein Mic1, Mic-1, C18orf8, MIC1|
|Target/Specificity||This MIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-428 amino acids from the Central region of human MIC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MIC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization (PubMed:29038162).|
|Cellular Location||Lysosome membrane. Late endosome membrane|
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Colon cancer-associated protein Mic1.
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