|Application ||FC, IHC-P, WB, E|
|Calculated MW||66035 Da|
|Antigen Region||308-335 aa|
|Other Names||Insulin-like growth factor-binding protein complex acid labile subunit, ALS, IGFALS, ALS|
|Target/Specificity||This IGFALS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the Central region of human IGFALS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IGFALS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.|
|Cellular Location||Secreted, extracellular space.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Leong S.R., Baxter R.C.Mol. Endocrinol. 6:870-876(1992)
Suwanichkul A.Endocrinology 141:833-838(2000)
Liu T., Qian W.-J.J. Proteome Res. 4:2070-2080(2005)
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