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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AK3 Antibody (N-term F210)   

AK3 Antibody (N-term F210)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AK3 Antibody (N-term F210) AP8132c
    Western blot analysis of anti-AK3 Pab (Cat. #AP8132c) in mouse kidney tissue lysate (35ug/lane). AK3(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P27144
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25268 Da
Antigen Region 23-53 aa
Additional Information
Gene ID 205
Other Names Adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170}, AK 4 {ECO:0000255|HAMAP-Rule:MF_03170}, 27410 {ECO:0000255|HAMAP-Rule:MF_03170}, 2746 {ECO:0000255|HAMAP-Rule:MF_03170}, Adenylate kinase 3-like {ECO:0000255|HAMAP-Rule:MF_03170}, GTP:AMP phosphotransferase AK4 {ECO:0000255|HAMAP-Rule:MF_03170}, AK4 {ECO:0000255|HAMAP-Rule:MF_03170}
Target/Specificity This AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human AK3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAK3 Antibody (N-term F210) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AK4 {ECO:0000255|HAMAP-Rule:MF_03170}
Function Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
Cellular Location Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03170, ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:19766732}
Tissue Location Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain
Research Areas
Citations (0)

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AK3 is a member of the adenylate kinase family of enzymes. This protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated.


Biochem. J. 358 (PT 1), 225-232 (2001)
Eur. J. Biochem. 261(2):509-517 (1999).
Brain Res. Mol. Brain Res. 62(2):187-195 (1998).
Genomics 13(3):537-542 (1992).
Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982).

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$ 325.00
$ 109.00
Cat# AP8132c
Availability: In Stock
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