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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (C-term)   

Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (C-term) AP8171b
    Western blot analysis of anti-GUCY1B3 Pab(AP8171b) in Y79 cell line lysate. GUCY1B3(arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02153
Other Accession NP_000848
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70514 Da
Antigen Region 589-619 aa
Additional Information
Gene ID 2983
Other Names Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit, GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Target/Specificity This GUCY1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between 589-619 amino acids of human GUCY1B3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGuanylyl Cyclase beta 1 (GUCY1B3) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUCY1B1 (HGNC:4687)
Function Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P16068}.
Tissue Location Detected in brain cortex and cerebellum (at protein level).
Research Areas
Citations (0)

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Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.


Russwurm, M., et al., J. Biol. Chem. 276(48):44647-44652 (2001).
Lucas, K.A., et al., Pharmacol. Rev. 52(3):375-414 (2000).
Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).
Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).
Giuili, G., et al., FEBS Lett. 304(1):83-88 (1992).

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$ 325.00
$ 109.00
Cat# AP8171b
Availability: In Stock
Bulk Size
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