|Application ||WB, FC, E|
|Calculated MW||42475 Da|
|Antigen Region||361-387 aa|
|Other Names||Killer cell immunoglobulin-like receptor 3DS1, MHC class I NK cell receptor, Natural killer-associated transcript 10, NKAT-10, KIR3DS1, NKAT10|
|Target/Specificity||This KIR3DS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-387 amino acids from the C-terminal region of human KIR3DS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KIR3DS1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor on natural killer (NK) cells for MHC class I molecules. Upon interaction with peptide-free HLA-F open conformer, triggers NK cell degranulation and anti-viral cytokine production.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in NK and T-cell lines but not in B- lymphoblastoid cell lines or in a colon carcinoma cell line|
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Provided below are standard protocols that you may find useful for product applications.
KIR3DS1 is the receptor on natural killer (NK) cells for HLA-C alleles. It does not inhibit the activity of NK cells.
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