|Application ||WB, IHC-P, FC, E|
|Calculated MW||39965 Da|
|Antigen Region||307-333 aa|
|Other Names||N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2|
|Target/Specificity||This FPRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-333 amino acids from the Central region of human FPRL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FPRL2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Yang,D., et.al., J. Leukoc. Biol. 72 (3), 598-607 (2002)
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