|Application ||IHC-P, WB, E|
|Calculated MW||116468 Da|
|Antigen Region||755-787 aa|
|Other Names||Caspase recruitment domain-containing protein 6, CARD6|
|Target/Specificity||This CARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human CARD6.|
|Precautions||CARD6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in apoptosis.|
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Provided below are standard protocols that you may find useful for product applications.
CARD6 is a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
Kim,S.S., et.al., Pathology 42 (1), 50-53 (2010)
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
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