|Application ||WB, IHC-P, FC, E|
|Calculated MW||56706 Da|
|Antigen Region||415-443 aa|
|Other Names||Beta-Ala-His dipeptidase, CNDP dipeptidase 1, Carnosine dipeptidase 1, Glutamate carboxypeptidase-like protein 2, Serum carnosinase, CNDP1, CN1, CPGL2|
|Target/Specificity||This CNDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the C-terminal region of human CNDP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CNDP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis|
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Provided below are standard protocols that you may find useful for product applications.
CNDP1 encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This protein contains trinucleotide (CTG) repeat length polymorphism in the coding region.
Craig,D.W., et.al., Diabet. Med. 26 (11), 1090-1098 (2009)
Mooyaart,A.L., et.al., Diabetes Res. Clin. Pract. 85 (3), 272-278 (2009)
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