|Application ||WB, IHC-P, FC, E|
|Other Accession||Q6PA06, Q95LN3|
|Calculated MW||66229 Da|
|Antigen Region||297-326 aa|
|Other Names||Atlastin-2, 365-, ADP-ribosylation factor-like protein 6-interacting protein 2, ARL-6-interacting protein 2, Aip-2, ATL2, ARL6IP2|
|Target/Specificity||This ATLA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the Central region of human ATLA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ATLA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:18270207, PubMed:19665976, PubMed:27619977).|
|Cellular Location||Endoplasmic reticulum membrane; Multi- pass membrane protein Note=Localizes at endoplasmic reticulum (ER) three-way tubular junctions (PubMed:27619977).|
|Tissue Location||Expressed in peripheral tissues (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ATLA2 is GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. This protein play a role in endoplasmic reticulum tubular network biogenesis.
Hu,J. Cell 138 (3), 549-561 (2009)
Rismanchi,N. Hum. Mol. Genet. 17 (11), 1591-1604 (2008)
Abel,A. Neurogenetics 5 (4), 239-243 (2004)
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