|Application ||WB, IHC-P, FC, E|
|Other Accession||P04694, Q8QZR1, Q58CZ9, NP_000344|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||50399 Da|
|Antigen Region||279-306 aa|
|Other Names||Tyrosine aminotransferase, TAT, L-tyrosine:2-oxoglutarate aminotransferase, TAT|
|Target/Specificity||This TAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the Central region of human TAT.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TAT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine.|
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Provided below are standard protocols that you may find useful for product applications.
TAT is a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate.
Liu, S., et al. Biosci. Rep. 29(2):103-109(2009)
Pasternack, S.M., et al. Br. J. Dermatol. 160(3):704-706(2009)
Maydan, G., et al. J. Inherit. Metab. Dis. 29(5):620-626(2006)
Charfeddine, C., et al. Mol. Genet. Metab. 88(2):184-191(2006)
Baharvand, H., et al. Int. J. Dev. Biol. 50(7):645-652(2006)
Natt, E., et al. Proc. Natl. Acad. Sci. U.S.A. 89(19):9297-9301(1992)
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