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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NOXA1 Antibody (C-term)   

NOXA1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NOXA1 Antibody (C-term) AP9567b
    Western blot analysis of NOXA1 Antibody (C-term) (Cat. #AP9567b) in MDA-MB435 cell line lysates (35ug/lane).NOXA1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86UR1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50933 Da
Antigen Region 449-478 aa
Additional Information
Gene ID 10811
Other Names NADPH oxidase activator 1, NOX activator 1, Antigen NY-CO-31, NCF2-like protein, P67phox-like factor, p51-nox, NOXA1, P51NOX
Target/Specificity This NOXA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the C-terminal region of human NOXA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNOXA1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOXA1
Synonyms P51NOX
Function Functions as an activator of NOX1, a superoxide- producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.
Cellular Location Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1
Tissue Location Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon
Research Areas
Citations (0)

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NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). The NOX activator NOXA1 can stimulate both NOX1 (MIM 300225) and NOX2 (CYBB; MIM 300481), but it appears to be more effective in activating NOX1 (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM].


?Niu, X.L., et al. Circulation 121(4):549-559(2010)
?Pacquelet, S., et al. J. Biol. Chem. 283(36):24649-24658(2008)
?Honjo, T., et al. Endothelium 15(3):137-141(2008)
?Kim, J.S., et al. J. Biol. Chem. 282(48):34787-34800(2007)
?Valente, A.J., et al. Free Radic. Biol. Med. 43(3):384-396(2007)
?Cheng, G., et al. J. Biol. Chem. 281(26):17718-17726(2006)

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Cat# AP9567b
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