|Application ||WB, E|
|Calculated MW||53812 Da|
|Antigen Region||347-377 aa|
|Other Names||FAD-dependent oxidoreductase domain-containing protein 1, 1---, FOXRED1|
|Target/Specificity||This FXRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-377 amino acids from the C-terminal region of human FXRD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FXRD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) (PubMed:20858599, PubMed:25678554). Involved in mid-late stages of complex I assembly (PubMed:25678554).|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein. Note=According to a report, it is associated with the matrix face of the mitochondrial inner membrane and does not contain any transmembrane region However, one transmembrane domain is clearly predicted by different methods (Probable).|
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Provided below are standard protocols that you may find useful for product applications.
Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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