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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   KTEL1 Antibody (C-term)   

KTEL1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KTEL1 Antibody (C-term) AP9678b
    Western blot analysis of KTEL1 Antibody (C-term) (Cat. #AP9678b) in T47D cell line lysates (35ug/lane). KTEL1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NBL1
Other Accession Q5E9Q1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46189 Da
Antigen Region 353-382 aa
Additional Information
Gene ID 56983
Other Names Protein O-glucosyltransferase 1, 241-, CAP10-like 46 kDa protein, hCLP46, KTEL motif-containing protein 1, Myelodysplastic syndromes relative protein, O-glucosyltransferase Rumi homolog, hRumi, Protein O-xylosyltransferase, POGLUT1, C3orf9, CLP46, KTELC1, MDSRP
Target/Specificity This KTEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-382 amino acids from the C-terminal region of human KTEL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKTEL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POGLUT1 (HGNC:22954)
Function Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (PubMed:27807076). Notch glucosylation does not affect Notch ligand binding (PubMed:21490058). Required during early development to promote gastrulation: acts by mediating O- glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity).
Cellular Location Endoplasmic reticulum lumen
Tissue Location Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine. Expressed in the epidermis, especially in the upper parts, stratum spinosum and stratum granulosum (at protein level).
Research Areas
Citations (0)

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Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Karadonta, A.V., et al. Int J Immunopathol Pharmacol 22(3):787-793(2009)
Teng, Y., et al. Gene 371(1):7-15(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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$ 325.00
$ 109.00
Cat# AP9678b
Availability: In Stock
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