|Application ||WB, IHC-P, E|
|Calculated MW||15240 Da|
|Antigen Region||93-122 aa|
|Other Names||Ly6/PLAUR domain-containing protein 1, Putative HeLa tumor suppressor, PHTS, LYPD1, LYPDC1|
|Target/Specificity||This LYPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human LYPD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LYPD1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha- 4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Yu, D.H., et al. Exp. Cell Res. 312(6):865-876(2006)
Choy, K.W., et al. Physiol. Genomics 25(1):9-15(2006)
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