|Application ||WB, FC, E|
|Calculated MW||12918 Da|
|Antigen Region||26-53 aa|
|Other Names||Progonadoliberin-2, Progonadoliberin II, Gonadoliberin-2, Gonadoliberin II, Gonadotropin-releasing hormone II, GnRH II, Luliberin II, Luteinizing hormone-releasing hormone II, LH-RH II, GnRH-associated peptide 2, GnRH-associated peptide II, GNRH2|
|Target/Specificity||This GNRH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-53 amino acids from the Central region of human GNRH2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNRH2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.|
|Tissue Location||Midbrain; expressed at significantly higher levels outside the brain (up to 30-fold), particularly in the kidney, bone marrow and prostate|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones.
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Poon, S.L., et al. Mol. Endocrinol. 23(10):1646-1656(2009)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Palmieri, R.T., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3567-3572(2008)
Poon, S.L., et al. Endocrinology 149(10):5162-5171(2008)
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