|Application ||WB, IHC-P, FC, E|
|Calculated MW||47231 Da|
|Antigen Region||423-450 aa|
|Other Names||Ammonium transporter Rh type B, Rhesus blood group family type B glycoprotein, Rh family type B glycoprotein, Rh type B glycoprotein, RHBG|
|Target/Specificity||This RHBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 423-450 amino acids from the C-terminal region of human RHBG.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHBG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a specific ammonium transporter.|
|Cellular Location||Basolateral cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein|
|Tissue Location||Specifically expressed in kidney. Also detected in liver and ovary.|
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Provided below are standard protocols that you may find useful for product applications.
RHBG encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini.
Han, K.H., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 297 (1), L153-L163 (2009)
Brown, A.C., et al. Am. J. Physiol. Renal Physiol. 296 (6), F1279-F1290 (2009)
Sohet, F., et al. J. Biol. Chem. 283(39):26557-26567(2008)
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